John K Botson Selected Research

Pegloticase

11/2022	Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy.
1/2022	Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response.
1/2022	Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series.
1/2021	Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR).
1/2021	The effect of immunomodulators on the efficacy and tolerability of pegloticase: a systematic review.
6/2020	Pegloticase hypersensitivity desensitisation: an outpatient, 3-bag, 12-step protocol.

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John K Botson Research Topics

Disease

5	Gout 11/2022 - 01/2021
2	Joint Diseases (Joint Disease) 01/2022 - 06/2020
1	Anaphylaxis (Anaphylactic Shock) 06/2020
1	Hypersensitivity (Allergy) 06/2020

Drug/Important Bio-Agent (IBA)

6	Pegloticase FDA Link 11/2022 - 06/2020
2	Uric Acid (Urate)IBA 11/2022 - 01/2022
2	Pharmaceutical PreparationsIBA 01/2022 - 06/2020
2	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 01/2021
2	AntibodiesIBA 01/2022 - 01/2022
1	Immunologic Factors (Immunomodulators)IBA 01/2022
1	Biological ProductsIBA 01/2021

Therapy/Procedure

4	Therapeutics 01/2022 - 06/2020
3	Immunomodulation 01/2022 - 01/2021
1	Drug Therapy (Chemotherapy) 06/2020